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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
17/11/2020 |
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Data da última atualização: |
17/11/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
COLNAGO, L. A.; TREVISOL, I. M.; RECH, D. V.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H. |
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Afiliação: |
LUIZ ALBERTO COLNAGO, CNPDIA; IARA MARIA TREVISOL, CNPSA; DAIANE VOSS RECH, CNPSA; LUCIMARA APARECIDA FORATO, CNPDIA; CIRLEI IGREJA DO NASCIMENTO MITRE, USP; JOSÉ PAULO GAGLIARDI LEITE, FIOCRUZ; RODRIGO GIGLIOTI, IZ; CINTIA HIROMI OKINO, CPPSE. |
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Título: |
Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020. |
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Páginas: |
1 - 9 |
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DOI: |
10.3390/ijerph17186456 |
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Idioma: |
Inglês |
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Conteúdo: |
The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and ecient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus ecacy of the proposed films. Polystyrene petri dishes were covered with a thin
layer of detergent formula. After drying, the films were exposed to dierent virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19. |
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Palavras-Chave: |
Antiviral; Coronavirus; Detergent; Film; Sanitization; Virucide. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02190naa a2200301 a 4500
001 2126684
005 2020-11-17
008 2020 bl uuuu u00u1 u #d
024 7 $a10.3390/ijerph17186456$2DOI
100 1 $aCOLNAGO, L. A.
245 $aSimple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge.$h[electronic resource]
260 $c2020
300 $a1 - 9
520 $aThe COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and ecient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus ecacy of the proposed films. Polystyrene petri dishes were covered with a thin layer of detergent formula. After drying, the films were exposed to dierent virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19.
653 $aAntiviral
653 $aCoronavirus
653 $aDetergent
653 $aFilm
653 $aSanitization
653 $aVirucide
700 1 $aTREVISOL, I. M.
700 1 $aRECH, D. V.
700 1 $aFORATO, L. A.
700 1 $aMITRE, C. I. N.
700 1 $aLEITE, J. P. G.
700 1 $aGIGLIOTI, R.
700 1 $aOKINO, C. H.
773 $tInternational Journal of Environmental Research and Public Health$gv. 17, a. 6456, 2020.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| Registros recuperados : 10 | |
| 3. |  | MITRE, C. I. N.; GOMES, B. F.; COLNAGO, L. A. Determinação do teor de íons paramagnéticos, Cu+2 e Ni+2 por RMN no domínio do tempo. In: JORNADA CIENTÍFICA - EMBRAPA SÃO CARLOS, 6., 2014, São Carlos, SP Anais... São Carlos: Embrapa Instrumentação: Embrapa Pecuária Sudeste, 2014. p. 36. Editores técnicos: João de Mendonça Naime, Caue Ribeiro, Maria Alice Martins, Elaine Cristina Paris, Paulino Ribeiro Villas Boas, Ladislau Marcelino Rabello. (Embrapa Instrumentação. Documentos, 57). Nas fórmulas Cu+2 e Ni+2 os símbolos [+2] são sobrescritos.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Instrumentação. |
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| 7. | | COBRA, P. F.; GOMES, B. F.; MITRE, C. I. N.; BARBOSA, L. L.; MARCONCINI, L. V.; COLNAGO, L. A. Measuring the solubility product constant of paramagnetic cations using time-domain nuclear magnetic resonance relaxometry. Microchemical Journal, [S. l.], v. 121, p. 14-17, 2015.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação. |
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| 8. | | WIESMAN, Z.; LINDER, C.; RESENDE, M. T.; AYALON, N.; LEVI, O.; BERNARDINELLI, O. D.; COLNAGO, L. A.; MITRE, C. I. N.; JACKMAN, R. 2D and 3D spectrum graphics of the chemical-morphological domains of complex biomass by low field proton NMR energy relaxation signal analysis. Energy & Fuels, v. 32, n. 4, 2018. 5090-5102| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação. |
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| 9. | | COLNAGO, L. A.; TREVISOL, I. M.; RECH, D. V.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H. Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge. International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020. 1 - 9| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 10. | | COLNAGO, L. A.; TREVISOL, I. M.; VOSS RECH, D.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H. Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge. International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020. 1 - 9| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação; Embrapa Suínos e Aves. |
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| Registros recuperados : 10 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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